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“ 09/28/2020 – Biomedical researchers Tuulia Hyötyläinen and Matej Orešič, at Örebro University, have published two studies connecting highly fluorinated chemicals to autoimmune diseases in children. In the studies, Hyötyläinen and Orešič, link per- and polyfluoroalkyl substances (PFAS’s) – with type 1 diabetes and celiac disease, or gluten intolerance in children. 

PFAS are man-made chemicals. There are about 5,000 PFAS, and they are used in numerous consumer products, such as furniture, adhesives, food packaging, coatings in clothing, and even fire-fighting foam.

In the celiac disease study, Hyötyläinen and Orešič show a connection between PFAS and celiac disease, by demonstrating that ‘high exposure to PFAS in the womb and in first years of life can accelerate the development of celiac disease in children,’ says Hyötyläinen. The studies appear in Environment Research. 

Their conclusions are based on analysis of the metabolization of small molecules in the body, and analysis of PFAS, coupled with a system’s biology approach to integration of complex study data, gathered from expectant mothers and children.

‘Exposure to harmful chemicals in early life, including prenatally, may offer an explanation for the changing incidence of these autoimmune diseases in developed countries and can be connected to other health risks,’ says Matej Orešič…”