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New research uncovers gene impacts of PFAS exposure in firefighters

Photo Credit: Kris Hanning / U of A Health Sciences Office of Communications

Read the full article by Steve Benowitz (U of A Health Sciences Office of Communications)

“Researchers at the University of Arizona Mel and Enid Zuckerman College of Public Health found that certain kinds of long-lasting chemicals firefighters are exposed to may affect the activity of genes linked to cancer and other diseases. The findings appear in the journal Environmental Research.

The study is among the first to connect common industrial chemicals called PFAS – per- and polyfluoroalkyl substances – to changes in microRNAs, or miRNAs, which are molecules that act as guardrails to help control gene expression. 

PFAS are found in a wide range of products, including upholstery, insulation, electronics, cleaning products, fabrics, non-stick cookware – and firefighting foam and gear. Firefighters can be at higher risk for certain cancers, and exposure to toxic chemicals may be one reason why. ” …

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